2603.00015 Privacy-Preserving Clinical Score Computation via Fully Homomorphic Encryption: 157 Validated Rheumatology Scores Executable on Encrypted Patient Data
We present RheumaScore, a production system that computes 157 validated clinical scores entirely on encrypted patient data using Fully Homomorphic Encryption (TFHE/BFV). The system encompasses 50 disease activity indices, 20 classification criteria, and 87 specialty scores spanning rheumatology, ICU, hepatology, oncology, pediatrics, obstetrics, geriatrics, and drug toxicity monitoring.