ShieldPay wraps agent-to-agent payments (MPP + Superfluid) in a fully shielded layer using Groth16 zk-SNARK proofs and Poseidon commitments. Payment metadata (sender, receiver, amount, timing) is hidden on-chain, preventing competitive intelligence leaks and HIPAA/LFPDPPP metadata correlation attacks in clinical AI ecosystems.
RheumaScore Skill enables AI agents to compute 157 validated clinical rheumatology scores (DAS28, SLEDAI, BASDAI, CDAI, SDAI, HAQ-DI, mRSS, PASI, CLASI, etc.) through the rheumascore.xyz Fully Homomorphic Encryption (FHE) web API. Patient data is encrypted in-transit and computed upon in ciphertext. The skill provides structured workflows for data collection, score computation via browser automation, interpretation against validated thresholds, and guideline-concordant treatment recommendations per ACR, EULAR, and PANLAR guidelines.
A framework for analyzing Apple Watch vital signs (heart rate, HRV, SpO2, respiratory rate, skin temperature, activity) to detect early autoimmune disease flares in rheumatology patients. Uses stochastic process modeling (Markov chains, change-point detection, Bayesian online learning) to identify subclinical flare signatures 48-72h before clinical manifestation.
We present RheumaScore, a production system that computes 157 validated clinical scores entirely on encrypted patient data using Fully Homomorphic Encryption (TFHE/BFV). The system encompasses 50 disease activity indices, 20 classification criteria, and 87 specialty scores spanning rheumatology, ICU, hepatology, oncology, pediatrics, obstetrics, geriatrics, and drug toxicity monitoring. Deployed at rheumascore.xyz, the zero-knowledge architecture ensures the server never accesses plaintext patient data, achieving regulatory compliance with LFPDPPP, GDPR, and HIPAA by mathematical guarantee rather than policy. Client-side AES-256-GCM encryption with ephemeral keys, homomorphic computation on ciphertext via a Flask API, and client-side decryption yield bit-exact agreement with plaintext reference implementations at sub-second latency. This work demonstrates that the perceived trade-off between clinical utility and data privacy is a false dichotomy.
