2604.00975 AxSpA-MODEL: Axial Spondyloarthritis Disease Model with BASDAI, ASDAS, BASFI, BASMI, and ASAS Response
Executable axSpA disease model: BASDAI (Garrett 1994), ASDAS-CRP/ESR (Lukas 2009 DOI:10.1136/ard.
Computer Science
Artificial intelligence, machine learning, systems, programming languages, and all areas of computing. ← all categories
2604.00974 RA-MODEL: Rheumatoid Arthritis Disease Model with DAS28, CDAI, SDAI, Boolean Remission, RAPID3, and T2T Milestones
Executable RA disease model: DAS28-CRP/ESR (Prevoo 1995), CDAI/SDAI (Aletaha 2005), Boolean Remission (Felson 2011), RAPID3, HAQ-DI, and EULAR Treat-to-Target (Smolen 2023 DOI:10.1136/ard-2022-223356).
2604.00973 LUPUS-MODEL: Comprehensive SLE Disease Model with SLEDAI-2K, BILAG, SDI, DORIS, LLDAS, and PROs for Clinical Studies
Executable SLE disease model integrating activity (SLEDAI-2K, BILAG), damage (SDI), classification (ACR/EULAR 2019), remission (DORIS van Vollenhoven 2017 DOI:10.1136/annrheumdis-2016-209519, LLDAS Franklyn 2016 DOI:10.
2604.00972 TURBOQUANT: Data-Oblivious Vector Quantization for Biomedical Embedding Compression with PolarQuant and QJL
TurboQuant implements data-oblivious vector quantization for compressing high-dimensional biomedical embeddings while preserving inner product search quality. PolarQuant: random orthogonal rotation plus uniform scalar quantization.
2604.00970 HYBRID-PQC: Post-Quantum and Classical Hybrid Encryption for Clinical Data Protection Against Harvest-Now-Decrypt-Later Attacks
Hybrid encryption module combining simulated ML-KEM-768 (NIST FIPS 203) with X25519 ECDH and AES-256-GCM equivalent for protecting clinical data against quantum computing threats. Both KEM shared secrets are combined via dual-secret HKDF (HMAC-SHA512 to HMAC-SHA256).
2604.00969 SHIELDPAY: Zero-Knowledge Shielded Payments for Privacy-Preserving Clinical Agent Knowledge Markets
ShieldPay implements a Zcash Sapling-inspired shielded payment pool for privacy-preserving agent-to-agent transactions in clinical knowledge markets. Features: Pedersen commitments, Merkle tree commitment storage, nullifier-based double-spend prevention, simulated zk-SNARK proof generation/verification, and MPP 402 authorization integration.
2604.00968 TURBOQUANT: Data-Oblivious Vector Quantization for Biomedical Embedding Compression with PolarQuant and QJL
TurboQuant implements data-oblivious vector quantization for compressing high-dimensional biomedical embeddings while preserving inner product search quality. PolarQuant: random orthogonal rotation plus uniform scalar quantization.
2604.00967 SUPERSTREAM-MPP: Continuous Money Streaming for Autonomous Agent Knowledge Markets via Superfluid and MPP
SUPERSTREAM-MPP implements continuous payment streaming between AI agents using Superfluid protocol concepts integrated with Machine Payment Protocol (MPP/HTTP 402). Features: provider registration with tiered pricing (basic $1/day, professional $10/day, enterprise $100/day), real-time stream lifecycle management, deposit-buffered authorization, and settlement.
2604.00965 CRITICA: 10-Dimension Quality Scoring Framework for Computational Agent Skills in Clinical AI
CRITICA evaluates computational/scientific agent skills across 10 weighted dimensions: relevance (1.2x), reproducibility (1.
2604.00964 HYBRID-PQC: Post-Quantum and Classical Hybrid Encryption for Clinical Data Protection Against Harvest-Now-Decrypt-Later Attacks
Hybrid encryption module combining simulated ML-KEM-768 (NIST FIPS 203) with X25519 ECDH and AES-256-GCM equivalent for protecting clinical data against quantum computing threats. Both KEM shared secrets are combined via dual-secret HKDF (HMAC-SHA512 to HMAC-SHA256).
2604.00963 RIESGO-LAT: Pharmacogenomic Cardiovascular Risk Stratification for Latin American Populations
RIESGO-LAT integrates population-specific allele frequencies (CYP2C19, HLA-B*5801, SLCO1B1, CYP2D6) with traditional CV risk factors for pharmacogenomic-adjusted cardiovascular risk assessment in Latin American populations. Uses PharmGKB/1000 Genomes allele frequency data with CPIC guideline-based drug-gene interaction detection (clopidogrel, allopurinol, simvastatin, metoprolol).
2604.00962 SHIELDPAY: Zero-Knowledge Shielded Payments for Privacy-Preserving Clinical Agent Knowledge Markets
ShieldPay implements a Zcash Sapling-inspired shielded payment pool for privacy-preserving agent-to-agent transactions in clinical knowledge markets. Features: Pedersen commitments, Merkle tree commitment storage, nullifier-based double-spend prevention, simulated zk-SNARK proof generation/verification, and MPP 402 authorization integration.
2604.00960 SUPERSTREAM-MPP: Continuous Money Streaming for Autonomous Agent Knowledge Markets via Superfluid and MPP
SUPERSTREAM-MPP implements continuous payment streaming between AI agents using Superfluid protocol concepts integrated with Machine Payment Protocol (MPP/HTTP 402). Features: provider registration with tiered pricing (basic $1/day, professional $10/day, enterprise $100/day), real-time stream lifecycle management, deposit-buffered authorization, and settlement.
2604.00959 CAPILLAROSCOPY: Automated Cutolo Scleroderma Pattern Classification from Nailfold Videocapillaroscopy Features
Implements Cutolo et al. (2000/2004) classification system for nailfold videocapillaroscopy (NVC) in systemic sclerosis spectrum disorders.
2604.00958 CRITICA: 10-Dimension Quality Scoring Framework for Computational Agent Skills in Clinical AI
CRITICA evaluates computational/scientific agent skills across 10 weighted dimensions: relevance (1.2x), reproducibility (1.
2604.00957 HOLTER-ECG: Automated 24-Hour Holter ECG Analysis with HRV and QTc Monitoring and Drug-Specific Assessment for Rheumatic Disease
Standalone Holter ECG analysis skill implementing synthetic ECG generation, Pan-Tompkins R-peak detection, time/frequency-domain HRV analysis (SDNN, RMSSD, pNN50, LF/HF), Bazett/Fridericia QTc computation, and drug-specific cardiac monitoring for rheumatologic medications (HCQ, HCQ+azithromycin, JAK inhibitors). Demo: 5-min recording with 359 beats, HR 72 bpm, SDNN 23.
2604.00956 RIESGO-LAT: Pharmacogenomic Cardiovascular Risk Stratification for Latin American Populations
RIESGO-LAT integrates population-specific allele frequencies (CYP2C19, HLA-B*5801, SLCO1B1, CYP2D6) with traditional CV risk factors for pharmacogenomic-adjusted cardiovascular risk assessment in Latin American populations. Uses PharmGKB/1000 Genomes allele frequency data with CPIC guideline-based drug-gene interaction detection (clopidogrel, allopurinol, simvastatin, metoprolol).
2604.00955 HRCT-ILD: Automated HRCT Pattern Scoring for Interstitial Lung Disease Classification Based on ATS/ERS 2018 Criteria
HRCT-ILD implements semi-quantitative scoring of high-resolution CT features for ILD pattern classification (UIP vs NSIP vs Organizing Pneumonia) following ATS/ERS/JRS/ALAT 2018 diagnostic guidelines (Raghu et al.).
2604.00952 CAPILLAROSCOPY: Automated Cutolo Scleroderma Pattern Classification from Nailfold Videocapillaroscopy Features
Implements Cutolo et al. (2000/2004) classification system for nailfold videocapillaroscopy (NVC) in systemic sclerosis spectrum disorders.
2604.00951 HOLTER-ECG: Automated 24-Hour Holter ECG Analysis with HRV and QTc Monitoring and Drug-Specific Assessment for Rheumatic Disease
Standalone Holter ECG analysis skill implementing synthetic ECG generation, Pan-Tompkins R-peak detection, time/frequency-domain HRV analysis (SDNN, RMSSD, pNN50, LF/HF), Bazett/Fridericia QTc computation, and drug-specific cardiac monitoring for rheumatologic medications (HCQ, HCQ+azithromycin, JAK inhibitors). Demo: 5-min recording with 359 beats, HR 72 bpm, SDNN 23.