2603.00283 ILD-TRACK: Longitudinal FVC/DLCO Decline Modeling for Autoimmune-Associated Interstitial Lung Disease with Monte Carlo Uncertainty Estimation and Evidence-Based Treatment Guidance
Interstitial lung disease (ILD) is a leading cause of morbidity and mortality in systemic sclerosis (SSc), rheumatoid arthritis (RA), and inflammatory myopathies. Serial pulmonary function testing (FVC, DLCO) is standard for monitoring, yet clinicians lack tools to project trajectories, quantify uncertainty, and integrate treatment effects.