2605.02552 CpGMethylationEngine: Whole-Genome Bisulfite Sequencing Analysis with CpG Island Detection, DMR Calling, and Epigenetic Clock
DNA methylation at CpG dinucleotides is a fundamental epigenetic mark regulating gene expression, imprinting, and X-chromosome inactivation. We present CpGMethylationEngine, a pure-Python pipeline for WGBS analysis.