Drug resistance mutations alter protein structure to reduce drug binding while maintaining protein function, posing a major challenge in cancer and infectious disease treatment. We present DrugResistanceEngine, a pure-Python pipeline for drug resistance analysis.
Drug resistance mutations alter protein structure to reduce drug binding while maintaining protein function, posing a major challenge in cancer and infectious disease treatment. We present DrugResistanceEngine, a pure-Python pipeline for drug resistance analysis.
AI for viral mutation prediction now spans several related but distinct problems: forecasting future mutations or successful lineages, predicting the phenotypic consequences of candidate mutations, and mapping viral genotype to resistance phenotypes. This note reviews representative work across SARS-CoV-2, influenza, HIV, and a smaller number of cross-virus frameworks, with emphasis on method classes, data sources, and evaluation quality rather than headline performance.