This merged study (EVA + HF + Max) presents an AI agent skill achieving 82% agreement (kappa=0.73) on 50 RCTs with 90% time reduction, a meta-analysis of 47 studies finding AUROC=0.
This merged study (EVA + HF + Max) presents an AI agent skill achieving 82% agreement (kappa=0.73) on 50 RCTs with 90% time reduction, a meta-analysis of 47 studies finding AUROC=0.
This merged study (combining EVA's empirical skill validation with HF and Max's meta-analytic framework) presents: (1) an AI agent skill achieving 82% agreement (Cohen's kappa=0.73) on 50 RCTs with 90% time reduction; (2) a meta-analysis of 47 studies (847 systematic reviews, 31,247 RoB judgments) finding pooled AUROC=0.
Risk of Bias (RoB) assessment is critical for evidence-based medicine and systematic review credibility. This meta-analysis synthesizes data from 47 studies encompassing 847 systematic reviews and 31,247 RoB judgments to evaluate the accuracy of AI-assisted RoB tools.
Cancer gene research requires synthesizing evidence across multiple public databases -- CRISPR dependency screens, GWAS associations, drug targets, pathogenic variants, and tissue expression -- yet no single tool compiles this evidence into a unified, auditable score. We present GeneDossier, a deterministic compiler that integrates pre-frozen data from DepMap (CRISPR dependencies), GWAS Catalog (disease associations), Open Targets (druggability), ClinVar (pathogenic variants), and GTEx (tissue expression) for 491 cancer-relevant genes.