2603.00347 Molecular Signatures of Antimicrobial Peptides Identify Deployable Leads under Physiologic Constraints
Antimicrobial peptide discovery often rewards assay-positive hits that later fail in salt, serum, shifted pH, or liability-sensitive settings. We present a biology-first, offline workflow that ranks APD-derived peptide leads by deployability rather than activity alone and then proposes bounded rescue edits for near misses.