2605.02678 TACRO-CYP5: CYP3A5-Guided Tacrolimus Exposure Risk Stratification in Autoimmune Disease
TACRO-CYP5 is a transparent bedside tacrolimus exposure-risk model for autoimmune disease. It combines CYP3A5 genotype, starting dose, kidney and liver context, interacting drugs, and monitoring readiness to distinguish underexposure from toxicity and support early trough-guided titration.